K L Tyler Selected Research

Reoviridae Infections

1/2005	Genes Induced by Reovirus Infection Have a Distinct Modular Cis-Regulatory Architecture.
1/2005	Mechanisms of reovirus-induced cell death and tissue injury: role of apoptosis and virus-induced perturbation of host-cell signaling and transcription factor activation.
9/2002	Reovirus-induced apoptosis requires both death receptor- and mitochondrial-mediated caspase-dependent pathways of cell death.
12/2001	Reovirus infection activates JNK and the JNK-dependent transcription factor c-Jun.
11/2001	Reoviruses and the host cell.
10/2001	Caspase 8-dependent sensitization of cancer cells to TRAIL-induced apoptosis following reovirus-infection.
9/2000	Reovirus-induced apoptosis is mediated by TRAIL.
4/2000	Reovirus-induced apoptosis requires activation of transcription factor NF-kappaB.

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K L Tyler Research Topics

Disease

8	Reoviridae Infections 01/2005 - 04/2000
4	Infections 05/2005 - 04/2000
2	Neoplasms (Cancer) 01/2005 - 10/2001
2	Virus Diseases (Viral Diseases) 12/2001 - 01/2001
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 07/2008
1	Meningitis 02/2006
1	Encephalitis (Encephalitis, Rasmussen) 02/2006
1	Weight Gain 01/2001
1	Myocarditis (Carditis) 01/2001

Drug/Important Bio-Agent (IBA)

5	Transcription Factors (Transcription Factor)IBA 01/2005 - 04/2000
4	NF-kappa B (NF-kB)IBA 05/2005 - 04/2000
3	Caspase 8 (Caspase-8)IBA 09/2002 - 09/2000
2	Proteins (Proteins, Gene)FDA Link 02/2006 - 01/2005
2	Mitogen-Activated Protein KinasesIBA 01/2005 - 12/2001
2	CaspasesIBA 09/2002 - 10/2001
2	Death Domain ReceptorsIBA 10/2001 - 09/2000
1	PrionsIBA 07/2008
1	Apoptosis Regulatory ProteinsIBA 09/2002
1	JNK Mitogen-Activated Protein KinasesIBA 12/2001
1	Phosphotransferases (Kinase)IBA 12/2001
1	isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketoneIBA 10/2001
1	Peptides (Polypeptides)IBA 10/2001
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 01/2001
1	Creatine Kinase (Creatine Phosphokinase)IBA 01/2001
1	CalpainIBA 01/2001
1	Biotin (Vitamin H)FDA Link 01/2001
1	Proteasome InhibitorsIBA 04/2000

Therapy/Procedure

2	Therapeutics 01/2005 - 01/2001
1	Long-Term Care 02/2006